Version 2.0
D B T G R

DataBase of Tunicate Gene Regulation
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About DBTGR

Ci-Wnt5

Gene product: Wnt family
Organism: C. intestinalis
Summary of experimentsCi-macho1 binds to 5'-GCCCCCCGCTG-3', the terminal Gs and the central CCC being critical for binding in vitro (Yagi 2004)

An additional Macho1 site was reported on the negative strand between position -2255 and -2245, but its sequence (5'-GCCCGTCGCGG-3') does not correspond with the JGI 2.00 sequence.
Activity reported

An unknown factor regulates Ci-Wnt5 in pole plasm in C. intestinalis (5)

Ci-macho1 regulates Ci-Wnt5 in muscle in C. intestinalis (15)
Sequences available
ID Gene Description Organism Dataset Dataset ID
s00410 Ci-Wnt5 -3000:+200 region of ci0100135747 C. intestinalis JGI 1 ci0100135747
s00411 Ci-Wnt5 -3000:+200 region of ci0200295373 C. intestinalis JGI 2 ci0200295373
s00412 Ci-Wnt5 -3000:+200 region of ENSCING00000000407 C. intestinalis JGI 2 ENSCING00000000407
References
  1. Davidson, B., Levine, M. (2003). "Evolutionary origins of the vertebrate heart: specification of the cardiac lineage in Ciona intestinalis." Proc Natl Acad Sci USA 100:11469-11473. (PUBMED)
  2. Yagi, K., Satoh, N., Satou, Y. (2004). "Identification of downstream genes of the ascidian muscle determinant gene Ci-macho1." Dev Biol 274:478-489. (PUBMED)