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D B T G R

DataBase of Tunicate Gene Regulation
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About DBTGR

Cs-ZicL

Gene product: ZicL
Organism: C. savignyi
Summary of experimentsTransient expression from 32 cell stage to early tailbud stage in cells that give rise to notochord, central nervous system and muscle.
Notochord:
32-cell stage: in A6.2, A6.4
64-cell stage: in A7.3, A7.7
early gastrula: in A8.5, A8.6, A8.13
Upstream of Cs-Bra in A-line.
Upstream of Cs-fibrn in A-line but not in B-line.
CNS:
32-cell stage: in A6.2, A6.4
64-cell stage: in A7.4, A7.8
early gastrula: in A8.17, A8.19, A8.25, B8.17, B8.19 (faint in A8.7, A8.8, A8.15, A8.16)
Upstream of Cs-ETR.
Muscle:
32-cell stage: in B6.2, B6.4
64-cell stage: in B7.3, B7.4, B7.5, B7.7, A7.8
early gastrula: in B7.5
No expression from mid gastrula.

Not controled by Cs-macho1.
Expression is regulated by nuclear accumulation of -catenin in A-line, but not in B-line (not directly, maybe downstream of Cs-FoxD).
Activity reported

An unknown factor regulates Cs-ZicL in notochord, central nervous system, muscle in C. savignyi (36)
References
  1. Imai, K., Satou, Y., Satoh, N. (2002). "Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos." Development 129:2723-2732. (PUBMED)