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D B T G R

DataBase of Tunicate Gene Regulation
Show all gene expression reporters      Show all publications

About DBTGR

Cs-TnI

Gene product: troponin I
Organism: C. savignyi
Summary of experimentsThe 363 bp from -750? to -387? are sufficient to activate expression in larval muscle.

The following highly conserved regions between C. savignyi and C. intestinalis were identified:
CH1: about -715 to -1735
CH2: about -525 to -475
CH3: about -445 to -415
CH4: about -410 to -390

CH1, CH2 and either CH3 or CH4 are required for activity.

Activation may be regulated by Ci-MDF or another bHLH activator.
Activity reported

An unknown factor regulates Cs-TnI in larval muscle, trunk ventral cells in C. savignyi (6, 17)
References
  1. Kusakabe T. (2005). "Decoding cis-regulatory systems in Ascidians." Zoolog Sci 22:129-146. (PUBMED)
  2. Johnson, D.S., Davidson, B., Drown, C.D., Smith, W.C., Sidow, A. (2004). "Noncoding regulatory sequences of Ciona exhibit strong correspondence between evolutionary constraint and functional importance." Genome Res 14:2448-2456. (PUBMED)