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DataBase of Tunicate Gene Regulation
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Gene product: myosin regulatory light chain
Organism: C. intestinalis
Summary of experimentsCi-Tbx6b and Ci-Tbx6c bind to 5'-GWTCACACCT-3' in vitro.

Ci-Tbx6b and Ci-Tbx6c are necessary for expression at the 110-cell stage. (Yagi 2005)
At the tailbud stage, in the absence of Ci-Tbx6b, expression is only found in the posterior blastomeres (Yagi 2005)
Activity reported

Ci-Tbx6b regulates Ci-MRLC3 in muscle in C. intestinalis (12)

Ci-Tbx6c regulates Ci-MRLC3 in muscle in C. intestinalis (1, 2)
Sequences available
ID Gene Description Organism Dataset Dataset ID
s00290 Ci-MRLC3 -3000:+200 region of ci0100130424 C. intestinalis JGI 1 ci0100130424
s00291 Ci-MRLC3 -3000:+200 region of ci0200281922 C. intestinalis JGI 2 ci0200281922
  1. Kusakabe T., Yoshida, R., Ikeda, Y., Tsuda, M. (2004). "Computational discovery of DNA motifs associated with cell type-specific gene expression in Ciona." Dev Biol 276:563-580. (PUBMED)
  2. Yagi, K., Takatori, N., Satou, Y., Satoh, N. (2005). "Ci-Tbx6b and Ci-Tbx6c are key mediators of the maternal effect gene Ci-macho1 in muscle cell differentiation in Ciona intestinalis embryos." Dev Biol 282:535-549. (PUBMED)
  3. Corbo, J.C., Fujiwara, S., Levine, M., Di Gregorio, A. (1998). "Suppressor of Hairless activates Brachyury expression in the Ciona embryo." Dev Biol 203:358-368. (PUBMED)