Copyright © 2005-2008, Human Genome Center,
Inst. Med. Sci., Univ. Tokyo. All rights reserved.
Version 2.0
D B T G R
DataBase of Tunicate Gene Regulation
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eg: snail, muscle, ci0100133445, ...
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transcription factors
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Genome region
eg: chr09q:3065382-3068581, ...
C. intestinalis
1.0
C. intestinalis
2.0
C. savignyi
1.0
C. savignyi
2.0
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About DBTGR
Ci-MRLC4
Gene product: myosin regulatory light chain
Organism:
C. intestinalis
Summary of experiments
Ci-Tbx6b and Ci-Tbx6c bind to 5'-GWTCACACCT-3' in vitro.
Ci-Tbx6b and Ci-Tbx6c are necessary for expression at the 110-cell stage. (Yagi 2005)
At the tailbud stage, in the absence of Ci-Tbx6b, expression is only found in the posterior blastomeres (Yagi 2005)
Activity reported
Ci-Tbx6b
regulates Ci-MRLC4 in
muscle
in
C. intestinalis
(
1
,
2
)
Ci-Tbx6c
regulates Ci-MRLC4 in
muscle
in
C. intestinalis
(
1
,
2
)
Sequences available
ID
Gene
Description
Organism
Dataset
Dataset ID
s00292
Ci-MRLC4
-3000:+200 region of ci0100135440
C. intestinalis
JGI 1
ci0100135440
s00293
Ci-MRLC4
-3000:+200 region of ci0200298121
C. intestinalis
JGI 2
ci0200298121
References
Kusakabe T., Yoshida, R., Ikeda, Y., Tsuda, M. (2004). "Computational discovery of DNA motifs associated with cell type-specific gene expression in Ciona."
Dev Biol
276
:563-580. (
PUBMED
)
Yagi, K., Takatori, N., Satou, Y., Satoh, N. (2005). "
Ci-Tbx6b
and
Ci-Tbx6c
are key mediators of the maternal effect gene
Ci-macho1
in muscle cell differentiation in
Ciona intestinalis
embryos."
Dev Biol
282
:535-549. (
PUBMED
)