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DataBase of Tunicate Gene Regulation
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Gene product: troponin T
Organism: C. intestinalis
Summary of experimentsAt most 600 bp are necessary (Davidson 2003)
Ci-Tbx6b binds to 5'-GWTCACACCT-3' in vitro.

Ci-Tbx6b is necessary for expression at the 110-cell stage. (Yagi 2005)
At the tailbud stage, in the absence of Ci-Tbx6b, expression is only found in the posterior blastomeres (Yagi 2005)
Activity reported

Ci-Tbx6b regulates Ci-TnT in larval tail muscle, trunk ventral cells, central nervous system, brain vesicle in C. intestinalis (1, 2, 5, 6)
Reporter construct expression
Name Gene Size Tissue Construct
Ci-TnT Ci-TnT 441 muscle
Sequences available
ID Gene Description Organism Dataset Dataset ID
s00069 Ci-TnT Mapping of the Ci-TnT expression vector insert C. intestinalis JGI 1 blat
s00145 Ci-TnT Mapping of the Ci-TnT expression vector insert C. intestinalis JGI 2 blat
s00376 Ci-TnT -3000:+200 region of ci0100146672 C. intestinalis JGI 1 ci0100146672
  1. Kusakabe T., Yoshida, R., Ikeda, Y., Tsuda, M. (2004). "Computational discovery of DNA motifs associated with cell type-specific gene expression in Ciona." Dev Biol 276:563-580. (PUBMED)
  2. Yagi, K., Takatori, N., Satou, Y., Satoh, N. (2005). "Ci-Tbx6b and Ci-Tbx6c are key mediators of the maternal effect gene Ci-macho1 in muscle cell differentiation in Ciona intestinalis embryos." Dev Biol 282:535-549. (PUBMED)
  3. Davidson, B., Levine, M. (2003). "Evolutionary origins of the vertebrate heart: specification of the cardiac lineage in Ciona intestinalis." Proc Natl Acad Sci USA 100:11469-11473. (PUBMED)
  4. Kusakabe T. (2005). "Decoding cis-regulatory systems in Ascidians." Zoolog Sci 22:129-146. (PUBMED)