Version 2.0
D B T G R

DataBase of Tunicate Gene Regulation
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About DBTGR

Ci-I-kappa-B

Gene product: I-kappa-B
Organism: C. intestinalis
Summary of experimentsCi-rel binds to the region from -779 to -770, but not to the one from -50 to -41.

Mutation or deletion of the sequence from -779 to -770 result in the suppression of the expression in the notochord and induction of the expression in the mesenchyme and epidermis.
Activity reported

Ci-rel regulates Ci-I-kappa-B in maternal, notochord in C. intestinalis (6, 19)
Sequences available
ID Gene Description Organism Dataset Dataset ID
s00227 Ci-I-kappa-B -3000:+200 region of ci0100148369 C. intestinalis JGI 1 ci0100148369
s00228 Ci-I-kappa-B -3000:+200 region of ci0200377278 C. intestinalis JGI 2 ci0200377278
s00229 Ci-I-kappa-B -3000:+200 region of ENSCING00000013573 C. intestinalis JGI 2 ENSCING00000013573
References
  1. Kusakabe T. (2005). "Decoding cis-regulatory systems in Ascidians." Zoolog Sci 22:129-146. (PUBMED)
  2. Kawai, N., Takahashi, H., Nishida, H., Yokosawa, H. (2005). "Regulation of NF-κB/rel by IκB is essential for ascidian notochord formation." Dev Biol 277:80-91. (PUBMED)